Education
2004 MSc: Exercise physiology (University of Jyväskylä, Finland)
2009 PhD: Exercise physiology (University of Jyväskylä, Finland). PhD Thesis
2013 Docent: Exercise physiology (University of Helsinki, Faculty of Medicine)
Past:
2005-2009 Doctoral Student
2010-2013 Academy of Finland Post Doctoral Researcher
Contact information
Faculty of Sport and Health Sciences
Biology of Physical Activity
University of Jyväskylä
Viveca 235, P.O. Box 35
40014 Jyväskylä, Finland
Tel: +358 40832 7001
E-mail: juha. hulmi (at) jyu.fi
Second Affiliation
Faculty of Medicine (Physiology)
University of Helsinki
Main research interests
- Muscle hypertrophy
- Muscle atrophy/wasting/cachexia
- Sports nutrition
- Exercise physiology
- Muscle metabolism and signaling
- Strength training
- Muscle medicine
Selected recent publications (others, see Pubmed):
As a post doc or senior researcher
Hulmi JJ ... Häkkinen K. The effects of intensive weight reduction on body composition and serum hormones in female fitness competitors. Frontiers in Physiology January 10 2017. http://journal.frontiersin.org/article/10.3389/fphys.2016.00689
Hulmi JJ, Hentilä J, ... Atalay M. Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress. Free Radical Biology & Medicine 99:308-322, 2016.
Nissinen TA ... Hulmi JJ. Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Scientific Reports 6, 2016.
Räsänen M., … Hulmi JJ, Kivelä R, Alitalo K. VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A. 2016 113(46):13144-13149.
Juha J. Hulmi... Heikki Peltonen. The effects of whey protein with or without carbohydrates on resistance training adaptations. J Int Soc Sports Nutr. 12, 48, 2015.
Ahtiainen J, … Hulmi JJ, Häkkinen K. Resistance Training-Induced Adaptations in Muscle Size and Strength are Heterogeneous. Age 38, 10, 2016.
Kainulainen H, ... Juha J. Hulmi. Myostatin/activin blocking combined with exercise reconditions skeletal muscle expression profile of mdx mice. Molecular and Cellular Endocrinology 2015 399, 131-142.
Holopainen T, … Hulmi JJ…, Kivelä R, Alitalo K. Endothelial Bmx tyrosine kinase activity is essential for myocardial hypertrophy and remodeling. Proc Natl Acad Sci U S A. 2015 Oct 1. pii: 201517810.
Ahtiainen JP, ... Hulmi JJ. Exercise type and volume alters signaling pathways regulating skeletal muscle glucose uptake and protein synthesis European Journal of Applied Physiology 115: 1835-1845, 2015.
Silvennoinen M, Ahtiainen JP, Hulmi JJ… Kainulainen H. PGC‐1 isoforms and their target genes are expressed differently in human skeletal muscle following resistance and endurance exercise. Physiological reports 3, e12563, 2015
Paulsen, G, ... Hulmi JJ,... Raastad T.Vitamin C and E supplementation alters protein signalling after a strength training session, but not muscle growth during 10 weeks of training. Journal of Physiology 15;592(Pt 24):5391-408 2014.
Rita Rinnankoski-Tuikka, Juha J. Hulmi, ... Heikki Kainulainen. Lipid droplet-associated proteins in high-fat fed mice with the effects of voluntary running and diet change. Metabolism 63: 1031-40, 2014
Riikka Kivelä,... Juha J. Hulmi, ... Kari Alitalo. VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol. Med. 6:307-21, 2014.
Juha J. Hulmi ... Ritvos O. Exercise restores decreased physical activity levels and increases markers of autophagy and oxidative capacity in myostatin/activin blocked mdx mice. American Journal of Physiology - Endocrinology and Metabolism 2013: 305: E171-E182.
Juha J. Hulmi ... Olli Ritvos. Muscle protein synthesis, mTORC1/MAPK/Hippo signaling and capillary density are altered by blocking of myostatin and activins. American Journal of Physiology - Endocrinology and Metabolism 2013: 304: E41-50.
Satu Pekkala, Petri Wiklund, Juha J. Hulmi, ... Sulin Cheng. Are Skeletal Muscle FNDC5 Gene Expression and Irisin Release Regulated by Exercise and Related to Health? Journal of Physiology, 591: 5393-5400, 2013.
Heikki Kainulainen, Juha J. Hulmi, Urho M. Kujala. Potential Role of Branched Chain Amino Acid (BCAA) Catabolism in Regulating Fat Oxidation. Exercise & Sport Sciences Reviews 41: 194-200, 2013.
Juha J. Hulmi ... Heikki Kainulainen. Altered REDD1, myostatin and Akt/mTOR/FoxO/MAPK Signaling in Streptozotocin-induced Diabetic Muscle Atrophy. American Journal of Physiology - Endocrinology and Metabolism 2012 302: E307-15
Selected papers as a PhD student:
Juha J. Hulmi, Vuokko Kovanen, Harri Selänne, William J. Kraemer, Keijo Häkkinen, Antti A. Mero. Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression. Amino Acids 37: 297-308, 2009.
Juha J. Hulmi, Jörgen Tannerstedt, Harri Selänne, Heikki Kainulainen, Vuokko Kovanen, Antti Mero. Resistance exercise and whey protein ingestion affects mTOR signaling pathway and myostatin in men. Journal of Applied Physiology, 106: 1720-1729, 2009.
Juha J. Hulmi, Juha P. Ahtiainen, Tuomas Kaasalainen, Eija Pöllänen, Keijo Häkkinen, Markku Alen, Harri Selänne, Vuokko Kovanen, Antti A. Mero. Post-exercise myostatin and activin IIb mRNA levels: effects of strength training. Medicine and Science in Sport and Exercise 39: 289-297, 2007.
Current main research projects
Academy of Finland 2014-2019. “Adequate muscle mass and aerobic capacity prolonging survival from muscle wasting: MassA”. I am investigating the extent and mechanisms how adequate muscle mass and aerobic capacity can prolong survival from a catastrophe situation (muscle wasting). https://www.jyu.fi/ajankohtaista/arkisto/2014/05/tiedote-2014-05-15-13-13-59-910255 and in english. First paper: http://www.nature.com/articles/srep32695
Muscle protein homeostasis: Proteostasis 2015-2020: This study investigates the effects of exercise, hypertrophy and atrophy on muscle protein homeostasis. First paper: https://www.ncbi.nlm.nih.gov/pubmed/27554968
Fitness and weight reduction 2015-2018. "The effects of weight reduction on physiology and systems biology on fitness competitors." This study combines the skills from the experts of exercise and nutrition physiology, genetics, systems biology and sports psychology together. First paper: http://journal.frontiersin.org/article/10.3389/fphys.2016.00689/abstract
Main research group in the Academy of Finland project:
Juha Hulmi, group leader
Tuuli Nissinen, PhD student
Jaakko Hentilä, PhD student
Anita Lampinen, Post doc
Juulia Lautaoja, graduate student / research assistant
Jouni Härkönen, graduate student
Mervi Tulonen, graduate student
Neea Järvinen, graduate student
Current active collaborators
Riikka Kivelä, Docent
Olli Ritvos, Docent
Heikki Kainulainen, Professor
Juha Ahtiainen, Docent
Markus Perola, Professor
Mika Silvennoinen, PhD
Mustafa Atalay, Docent
Fabio Penna, PhD
Keijo Häkkinen, Professor
Antti Mero, Professor
Kari Alitalo, Professor
More information
For more information, see my scientific blog-page, Lihastohtori (in Finnish).
You can also follow me on Facebook, Google Scholar and LinkedIn and ResearchGate. Some of my appearances in media are listed here.
You should also check my recent Lihastohtori-book (In Finnish).
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