Education
2004 MSc: Exercise physiology (University of Jyväskylä, Finland)
2009 PhD: Exercise physiology (University of Jyväskylä, Finland). PhD Thesis
2013 Docent: Exercise physiology (University of Helsinki, Faculty of Medicine)
Past:
2005-2009 Doctoral Student
2010-2013 Academy of Finland Post Doctoral Researcher
2014-2019 Academy of Finland Research Fellow
Contact information
Faculty of Sport and Health Sciences
Neuromuscular Research Center and Gerontology Research Center
Biology of Physical Activity
University of Jyväskylä
Viveca 235, P.O. Box 35
40014 Jyväskylä, Finland
E-mail: juha. hulmi (at) jyu.fi
Main research interests
- Muscle hypertrophy
- Muscle atrophy/wasting/cachexia
- Sports nutrition
- Exercise physiology
- Muscle metabolism and signaling
- Strength training
- Muscle and sports medicine
- Weight loss / fitness
Selected recent publications (others, see Pubmed):
As a PI or post doc (* = equal contribution)
Hulmi JJ et al. Muscle NAD+ depletion and Serpina3n as molecular determinants of murine cancer cachexia-the effects of blocking myostatin and activins. Mol Metab. 2020 41:101046.
Hentilä J, Hulmi JJ et al. Sprint and Strength Training Modulates Autophagy and Proteostasis in Aging Sprinters. Med Sci Sports Exerc. 2020
Sarin HV ... Kristiansson K*, Hulmi JJ*, Perola M*. Substantial fat mass loss reduces low-grade inflammation and induces positive alteration in cardiometabolic factors in normal-weight individuals. Scientific Reports 2019 9, 3450.
Wackerhage H, Schoenfeld BJ, Hamilton DL, Lehti M, and Hulmi JJ. Stimuli and sensors that initiate skeletal muscle hypertrophy following resistance exercise. Journal of Applied Physiology 2019 126, 30-43.
Nissinen T ... Hulmi JJ. Treating cachexia using sACVR2B-Fc improves survival, alters mTOR localization and attenuates liver and spleen responses. Journal of Cachexia Sarcopenia Muscle. 2018 9, 514-529.
Hentila J, Ahtiainen JP ... Hulmi JJ. Autophagy is induced by resistance exercise in young men but unfolded protein response is induced regardless of age. Acta Physiologica. 2018 224(1):e13069.
Hulmi JJ*, Nissinen T* et al. Prevention of chemotherapy-induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle. J Cachexia Sarcopenia Muscle. 9, 417-432, 2018,
Hulmi JJ et al. The effects of intensive weight reduction on body composition and serum hormones in female fitness competitors. Frontiers in Physiology. January 10 2017.
Nissinen TA ... Hulmi JJ. Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Scientific Reports 6, 2016.
Räsänen M., … Hulmi JJ, Kivelä R, Alitalo K. VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A. 2016 113(46):13144-13149.
Hulmi JJ et al. The effects of whey protein with or without carbohydrates on resistance training adaptations. J Int Soc Sports Nutr. 12, 48, 2015.
Ahtiainen J … Hulmi JJ, Häkkinen K. Resistance Training-Induced Adaptations in Muscle Size and Strength are Heterogeneous. Age 38, 10, 2016.
Selected papers as a PhD student:
Hulmi JJ et al. Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression. Amino Acids 37: 297-308, 2009.
Hulmi JJ et al. Resistance exercise and whey protein ingestion affects mTOR signaling pathway and myostatin in men. Journal of Applied Physiology, 106: 1720-1729, 2009.
Hulmi JJ et al. Post-exercise myostatin and activin IIb mRNA levels: effects of strength training. Medicine and Science in Sport and Exercise 39: 289-297, 2007.
Current or recently finished main research projects
Academy of Finland 2014-2019 (/2020). “Adequate muscle mass and aerobic capacity prolonging survival from muscle wasting: MassA”. I have been investigating the extent and mechanisms how adequate muscle mass and aerobic capacity can prolong survival from a catastrophe situation (muscle wasting). See publications: 1, 2, 3, 4, 5, 6, 7, 8, 9
Muscle protein homeostasis: Proteostasis 2015-2020: This study investigates the effects of exercise, hypertrophy and atrophy on muscle protein homeostasis. See publications: 1, 2, 3, 4
Fitness and weight reduction 2015-. We study the effects of weight reduction on physiology and systems biology on fitness competitors. This study combines the skills from the experts of exercise and nutrition physiology, genetics, systems biology and sports psychology together. See publications: 1, 2, 3
In vitro exercise 2019-. We investigate using C-Pace EPS system the effects of muscle contraction on "exerkines".
Main research group in the Academy of Finland project:
A Group photo (23.8.2017) of my Academy of Finland project MassA. The Group is named "Another Group".
In the photo Jaakko Hentilä (PhD student), Juha Hulmi, Juulia Lautaoja (PhD student), Tuuli Nissinen (PhD student) and Anita Lampinen (Post doc).
I am also PhD supervisor of Heikki Sarin and Ville Isola.
More information
For more information, see my scientific blog-page, Lihastohtori (in Finnish).
You can also follow me on Facebook, Google Scholar and LinkedIn and ResearchGate. Some of my appearances in media are listed here.
You should also check my recent Lihastohtori-book (In Finnish).
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